Sunday, July 26, 2015

Alzheimer’s disease and coffee

Over the past few years there has been increasing interest in the health benefits of coffee, as coffee consumption has been linked with better cognitive functioning and a lower risk of Alzheimer’s disease.

There are several studies showing that people who drink two or four cups of coffee each day are less likely to develop Alzheimer’s dementia that are people who do not drink coffee.

Scientific studies have shown that caffeine and other substances in coffee have a number of different effects on the brain that would be expected to improve one’s chances of avoiding dementia.

In one findings, shows that caffeinated coffee induces an increase in blood levels of growth factors GCSF (granulocyte colony stimulating factor). Researchers note that moderate coffee drinking (4 to 5 cups per day) starting in middle age may provide protection for Alzheimer’s symptoms and disease.

Based on animal study data, caffeine may prevent Alzheimer’s disease by protecting against beta-amyloid toxicity through adenosine A1 receptor inhibition.

Coffee also reduces inflammation and improves the health of the endothelial lining of arteries. Some substances in coffee also have significant antioxidant effects.

Together these beneficial effects of coffee offer the brain protection from some of the primary pathological processes that cause Alzheimer’s and other neurodegenerative disease to progress.

In Canadian Study of Health and Aging, daily coffee drinking lowered Alzheimer’s risk by 31 percent during five years follow-up.

In addition to direct preventive effects against Alzheimer’s disease, caffeine consumption may also indirectly inhibit cognitive decline via prevention of type II diabetes, a disease associated with accelerated rates of cognitive decline.
Alzheimer’s disease and coffee 

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