Numerous epidemiological studies have focused in the relationship between coffee consumption and cancer incidence at various sites, particularly the bladder, pancreas, colorectum, stomach, breast and ovary.
The role of coffee consumption and risk of cancer has been controversial. In a meta analysis of lung cancer incidence, five prospective studies and eight case control studies involving 110,258 individuals with 5347 lung cancer cases indicated a significant positive association between highest coffee intake and lung cancer.
Coffee consumption may look like it is related to lung cancer but this apparent association is most likely the result do the fact that coffee drinking is associated with cigarette smoking.
In another research the link between coffee and breast cancer may stem from antagonistic impact that caffeine has on fibrocystic breast lumps; however, many studies have found no relationship between caffeine and breast cancer.
There is limited evidence that coffee drinking is carcinogenic in the urinary bladder, lack of evidence of carcinogenicity in the breast and large bowel, and inadequate evidence of carcinogenicity in the pancreas, ovary and other sites.
Coffee and cancer
