Coffee reduce risk of cancer

Coffee is widely consumed worldwide, and is substantial evidence from both laboratory and animal studies suggest its ability to reduce the risk of cancer.

Cancer is one of the most feared diseases. The carcinogenic potential of coffee has been investigated in several long term animal bioassays.

Studies suggest those who enjoy a cup of coffee every day or nearly daily have a lower risk for liver cancer than those who rarely sip a cup.

Feeding high levels of coffee as part of the diet did not produce tumors in either rats or mice (Nehling & Debry 1996).

On the contrary, some studies reported that instant coffee resulted in a decreased incidence of spontaneous tumors (Stadler 1990). The presence of antioxidants in coffee can explain the anticancer property of the beverage, but there are other compounds which might be involved.

According to the scientists, caffeine and caffeic acid, major coffee constituents have been shown to suppress mammary tumor formation in animal models and to inhibit DNA methylation in human breast cancer cells, respectively.

Coffee may also reduce risk through decreasing inflammation and influencing estrogen metabolism.

Research by National Institute of Environmental Health Sciences, North Carolina reported that cafestol and kahweol, which are naturally occurring diterpenes in coffee, have proved to have anti-carcinogenic properties.
Coffee reduce risk of cancer

Coffee and cancer

Numerous epidemiological studies have focused in the relationship between coffee consumption and cancer incidence at various sites, particularly the bladder, pancreas, colorectum, stomach, breast and ovary.

The role of coffee consumption and risk of cancer has been controversial. In a meta analysis of lung cancer incidence, five prospective studies and eight case control studies involving 110,258 individuals with 5347 lung cancer cases indicated a significant positive association between highest coffee intake and lung cancer. 

Coffee consumption may look like it is related to lung cancer but this apparent association is most likely the result do the fact that coffee drinking is associated with cigarette smoking.

In another research the link between coffee and breast cancer may stem from antagonistic impact that caffeine has on fibrocystic breast lumps; however, many studies have found no relationship between caffeine and breast cancer.

There is limited evidence that coffee drinking is carcinogenic in the urinary bladder, lack of evidence of carcinogenicity in the breast and large bowel, and inadequate evidence of carcinogenicity in the pancreas, ovary and other sites.
Coffee and cancer