Coffee can reduce the incidence of gout

Coffee is a sort of soft beverage widely consumed in the world. For example, nearly half of the Japanese adults drink coffee on a daily basis, and over 50% of Americans consume an average coffee intake of 1–2 cups per day.

Gout is the most common inflammatory arthritis in adult males. This disease starts with unexpected attacks, but can become chronic with flare ups that cause joints to suddenly become red, hot, swollen, and tender.

Coffee is one of the most widely consumed beverages in the world and may affect the risk of gout via various mechanisms, including reducing serum uric acid levels and influencing insulin resistance.

Coffee is thought to reduce gout risk by lowering uric acid levels through several mechanisms. Coffee may lower uric acid levels by increasing the rate that human body excretes uric acid. Coffee is also thought to compete with the enzyme that breaks down purines in the body.

Components of coffee other than caffeine may affect the risk of gout by influencing insulin resistance and circulating insulin levels. Higher long-term coffee intake is associated with lower insulin levels and increased insulin sensitivity. Furthermore, several studies and a recent meta-analysis consistently found that coffee consumption was inversely associated with the risk of type 2 diabetes.

Chlorogenic acid and other antioxidants help reduce blood levels of the hormone, insulin. Levels of insulin and uric acid (the chemical that triggers gout) are closely related, and insulin concentrations from coffee consumption may lead to a lower risk of hyperuricemia and gout. When insulin levels are low, uric acid tends to be lower, too.

Hyperuricaemia is commonly recognised as a risk factor for many chronic diseases such as hypertension, diabetes, cardiovascular disease, metabolic syndrome, chronic kidney disease11 and insulin resistance.
Coffee can reduce the incidence of gout